Up until recently, organic cotton pajamas had been enough to keep our 18 month old with eczema sleeping through the night without much itching… but, recently he started itching so bad at night that he was waking up crying. I bought one pair of these pajamas and he’s back to sleeping 12 hours through the night with minimal itching and sleeping 2.5-3hr at nap time again too. He’s been yawning much less when he’s awake, which I’m assuming is because he’s probably getting better quality sleep from less itching. When these are being washed and he’s back in cotton pjs, he itches a lot more. This material really does seem to help and I’m so thankful for it! His skin looks much better when he wears them. He is 27 pounds and we bought the 1-2yr artic.